Test: An inventory of the aspergillus secretome

Overview

Protein secretion usually requires the presence of a N- terminal signal peptide (SP) and by scanning for this feature using available highly accurate SP-prediction tools, the fraction of potentially secreted proteins can be directly predicted. We were able to improve the in silico inventory of Aspergillus niger secretory proteins by combining different gene-model predictions from neighbouring Aspergilli and thereby avoiding prediction conflicts associated with inaccurate gene-models. An experimental validation of the predicted proteome confirmed in silico predictions.

Programme: IBISBA Workshop

SEEK ID: https://sandbox10.fairdomhub.org/projects/3

Public web page: http://www.manchester.ac.uk

Organisms: Aspergillus niger

IBISBA PALs: No PALs for this Project

Project start date: 1st Mar 2025

Project end date: 31st Dec 2028

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